How the Founding Fathers saw the second amendment.
An armed populace is able to protect itself from overreaching government and provides the sound foundation of citizen militias.
How things would actually work today if such a sanctioned usage of the 2nd amendment were to happen:
A general insurrection arises from the populace due to (event), and people reach for their 2nd amendment firearms. The police, local, state, and federal, treat this as what it is: a crime-wave, and respond with the full force of law-enforcement. With social media monitoring, telecomms interception, electronic interception, drone monitoring of movements, and a concerted effort to interrupt supply chains and disrupt ideological coordination.
Who needs guns, they've been deprecated already. The intent of the 2nd amendment has already been superseded. It's biggest effect is to turn random stabbings into random shootings, not provide a periodic overthrow of the government.